After over a century of robust health, disease rears its ugly head again. MarsCo pushes toward a charity-based health care system. Genetic therapy titan Genotype takes the brunt of the blame. It’s nearly 10 years before science rebottles this particular demon.

Reference: Mars history, HSD 2.0, with some references in Genotype discussions and Progenitus creation story

Date Notes: Early 100s, likely before ledger, but no firm dates